N-({(2S,3S)-3-[(benzylamino)carbonyl]oxiran-2-yl}carbonyl)-L-isoleucyl-L-proline

N-({(2S,3S)-3-[(benzylamino)carbonyl]oxiran-2-yl}carbonyl)-L-isoleucyl-L-proline is an experimental small molecule dipeptide compound. It is a synthetic inhibitor of cathepsin B, a lysosomal cysteine protease implicated in various pathological processes including cancer progression and metastasis. The compound has been studied primarily as a biochemical tool for structural and mechanistic studies of cathepsin B inhibition but has not advanced to clinical development or approval for any therapeutic indication[1][4][6]. Its mechanism involves covalent binding to the active site of cathepsin B via its epoxide (oxirane) moiety.

Other names

N-{[(2S,3S)-3-(benzylcarbamoyl)-2-oxiranyl]carbonyl}-L-isoleucyl-L-prolineL-Proline, N-[[(2S,3S)-3-[[(phenylmethyl)amino]carbonyl]oxiranyl]carbonyl]-L-isoleucyl-CATB_BOVIN